Antibody‐Based Therapeutics: Ultrasensitive NIR‐SERRS Probes with Multiplexed Ratiometric Quantification for In Vivo Antibody Leads Validation (Adv. Healthcare Mater. 4/2018). Issue 4 (21st February 2018)

• Record Type: Journal Article
• Authors: Kang, Homan; Jeong, Sinyoung; Jo, Ahla; Chang, Hyejin; Yang, Jin‐Kyoung; Jeong, Cheolhwan; Kyeong, San; Lee, Youn Woo; Samanta, Animesh; Maiti, Kaustabh Kumar; Cha, Myeong Geun; Kim, Taek‐Keun; Lee, Sukmook; Jun, Bong‐Hyun; Chang, Young‐Tae; Chung, Junho; Lee, Ho‐Young; Jeong, Dae Hong; Lee, Yoon‐Sik
• Is Part Of: Advanced healthcare materials. Volume 7:Issue 4(2018)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2018-02-21
• Subjects: antibody validation -- near‐infrared -- quantification -- SERS probes; Biomedical materials -- Periodicals; 610.28
• DOI: 10.1002/adhm.201870019
• Languages: English
• ISSNs: 2192-2640

Abstract

Abstract : In article number1700870, Yoon‐Sik Lee and co‐workers demonstrate in vivo validation process of candidate antibodies against human colon cancer, using a ratiometric quantification method. The validation is performed on a single mouse and analyzed by multiplexed surface‐enhanced resonance Raman scattering (SERRS) with ultrasensitive and near‐infrared (NIR)‐active SERRS nanoprobes (NIR‐SERRS dots).