Pernio as the presenting sign of blast crisis in acute lymphoblastic leukemia. Issue 1 (12th December 2017)

• Record Type: Journal Article
• Authors: Park, Kelly K.; Tayebi, Bailey; Uihlein, Lily; Speiser, Jodi; Mir, Adnan; Gerami, Pedram; Mancini, Anthony; Kim, Wendy
• Is Part Of: Pediatric dermatology. Volume 35:Issue 1(2018)
• Page Start: e74
• Page End: e75
• Publication Date: 2017-12-12
• Subjects: acute lymphoblastic leukemia -- chilblains -- leukemia cutis -- pernio; Pediatric dermatology -- Periodicals; Children -- Diseases -- Periodicals; 618.925
• DOI: 10.1111/pde.13366
• Languages: English
• ISSNs: 0736-8046

Abstract

Abstract: A previously healthy 5‐year‐old girl presented with acute onset of blue toes and red spots on the nose and fingers. The striking nature of these lesions, along with the finding of submandibular lymphadenopathy, prompted further evaluation. Laboratory findings were remarkable for anemia, high transaminase levels, and high blast count. Histopathologic findings were consistent with early pernio. Further examination revealed acute B‐cell lymphoblastic leukemia. Treatment of the leukemia led to resolution of the pernio.