Relation between lymphocyte to monocyte ratio and short‐term mortality in patients with acute pulmonary embolism. (20th October 2016)

• Record Type: Journal Article
• Authors: Ertem, Ahmet Goktug; Yayla, Cagri; Acar, Burak; Kirbas, Ozgur; Unal, Sefa; Uzel Sener, Melahat; Akboga, Mehmet Kadri; Efe, Tolga Han; Sivri, Serkan; Sen, Fatih; Gokaslan, Serkan; Topaloglu, Serkan
• Is Part Of: Clinical respiratory journal. Volume 12:Number 2(2018)
• Page Start: 580
• Page End: 586
• Publication Date: 2016-10-20
• Subjects: acute pulmonary embolism -- inflammation -- lymphocyte to monocyte ratio -- mortality; Respiratory organs -- Diseases -- Periodicals; Respiratory organs -- Periodicals; 616.24
• DOI: 10.1111/crj.12565
• Languages: English
• ISSNs: 1752-6981

Abstract

Abstract: Introduction: The relationship between inflammation and mortality after acute pulmonary embolism (APE) has previously been investigated with different variables (platelet/lymphocyte ratio, etc). Objectives: We investigated the predictive value of lymphocyte to monocyte ratio (LMR) for mortality in first 30 days after APE. Methods: The study population included 264 APE patients of which 230 patients were survivors, 34 patients were non‐survivors. Results: LMR was significantly lower in non‐survivors after APE ( P < .001). Neutrophil‐to‐lymphocyte ratio (NLR) was higher in non‐survivors after APE ( P < .001). Platelet‐to‐lymphocyte (PLR) had no significance between both groups ( P : .241). Simplified pulmonary embolism severity index and LMR were independent predictors of mortality in patients with APE ( P : .008 and P : .001, respectively). Conclusion: LMR as a novel marker of inflammation seemed to be an independent predictor of short‐term mortality in patients with APE.