Sultams: Recent Syntheses and Applications. Issue 8 (23rd January 2018)

• Record Type: Journal Article
• Authors: Debnath, Sudarshan; Mondal, Shovan
• Is Part Of: European journal of organic chemistry. Issue 8(2018)
• Page Start: 933
• Page End: 956
• Publication Date: 2018-01-23
• Subjects: Sultams -- Synthesis -- Reaction mechanisms -- Asymmetric synthesis -- Biological activity -- Synthetic applications -- Biological applications; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1002/ejoc.201701491
• Languages: English
• ISSNs: 1434-193X

Abstract

Abstract : Sultams are very important scaffolds both in medicinal chemistry and in synthetic organic chemistry. Very important methodologies for the asymmetric and non‐asymmetric synthesis of sultams, including asymmetric synthesis with memory of chirality (MOC), have recently been developed. Nowadays sultams are tremendously widely applied both in the medicinal field and in the synthetic field for the synthesis of different natural and non‐natural heterocycles. This review covers the recent development (2011–June 2017) of powerful methodologies for the synthesis of sultams and their applications in various fields during this period. A critical view of the mechanisms of the developed methodologies together with the scope and limitations of these methods add an extra dimension to the text. Abstract : Recent powerful methodologies for the asymmetric and non‐asymmetric synthesis of sultams are reported. Synthetic and biological applications of sultams are also discussed.