In vitro apatite formation on porous anodic alumina induced by a phosphorylation treatment. (September 2014)

• Record Type: Journal Article
• Authors: Li, Xiaohong; Ni, Siyu; Webster, Thomas J
• Is Part Of: Journal of biomaterials applications. Volume 29:Number 3(2014:Sep.)
• Page Start: 321
• Page End: 328
• Publication Date: 2014-09
• Subjects: Porous anodic alumina -- phosphorylation treatment -- functional groups -- bone-like apatite -- bioactive; Biomedical engineering -- Periodicals; Biomedical materials -- Periodicals; 610.28
• DOI: 10.1177/0885328214526765
• Languages: English
• ISSNs: 0885-3282

Abstract

In this study, a phosphorylation treatment of porous anodic alumina (PAA) was performed by wet impregnation in phosphoric acid and a subsequent heat treatment. The PAA and phosphorylated PAA specimens were analyzed using a field emission scanning electron microscope, an energy-dispersive X-ray spectrometer, and Fourier transform infrared spectroscopy. The apatite-forming ability of the phosphorylated PAA was evaluated by soaking the specimens in simulated body fluid for 1, 3, and 7 days. The surface microstructures and chemical property changes after soaking in simulated body fluid were again characterized by field emission scanning electron microscope, energy-dispersive X-ray spectrometer, and Fourier transform infrared spectroscopy. Results of this study demonstrated that the functional –PO4 groups introduced onto the PAA surface dramatically promoted the deposition of bone-like apatite on PAA. The results from this study indicated that the phosphorylation treatment of anodic alumina is an effective method for inducing bone-like apatite formation, and this phosphorylated PAA can be a promising candidate to be used as bioactive surface coatings on implant metals and alloys for orthopedic and dental applications.