A continuous-flow synthesis of primary amides from hydrolysis of nitriles using hydrogen peroxide as oxidant. Issue 13 (29th March 2018)
- Record Type:
- Journal Article
- Title:
- A continuous-flow synthesis of primary amides from hydrolysis of nitriles using hydrogen peroxide as oxidant. Issue 13 (29th March 2018)
- Main Title:
- A continuous-flow synthesis of primary amides from hydrolysis of nitriles using hydrogen peroxide as oxidant
- Authors:
- Zhan, Wei
Ji, Ling
Ge, Ze-mei
Wang, Xin
Li, Run-tao - Abstract:
- Abstract: A continuous-flow synthesis of primary amides from hydrolysis of nitriles using hydrogen peroxide as oxidant has been developed. Using this procedure, a variety of nitriles could be smoothly transformed into the desired primary amides in good to excellent yields. The mild reaction conditions and the flowing reaction system greatly improved the safety and make the reaction easy to scale up. Graphical abstract:
- Is Part Of:
- Tetrahedron. Volume 74:Issue 13(2018)
- Journal:
- Tetrahedron
- Issue:
- Volume 74:Issue 13(2018)
- Issue Display:
- Volume 74, Issue 13 (2018)
- Year:
- 2018
- Volume:
- 74
- Issue:
- 13
- Issue Sort Value:
- 2018-0074-0013-0000
- Page Start:
- 1527
- Page End:
- 1532
- Publication Date:
- 2018-03-29
- Subjects:
- Hydrolysis of nitriles -- Continuous flow chemistry -- Green chemistry -- Hydrogen peroxide
Chemistry, Organic -- Periodicals
547.005 - Journal URLs:
- http://www.elsevier.com/journals ↗
- DOI:
- 10.1016/j.tet.2018.02.017 ↗
- Languages:
- English
- ISSNs:
- 0040-4020
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 8796.850000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 5897.xml