I2-catalyzed one-pot synthesis of benzofuro/thieno[2, 3-b]pyrrole motifs. Issue 13 (29th March 2018) - Chacko, Priya
Abstract: A novel I2 -catalyzed one-pot multicomponent protocol for the synthesis of a variety of elusive furo[2, 3- b ]pyrrole and thieno[2, 3- b ]pyrrole libraries has been established. To date, cyclization among alkanone, hydrazine and 2-bromobenzofuran or 2-bromobenzo[ b ]thiophene has not been explored in one-pot. Thus, the proposed single step protocol provides a versatile alternative to existing routes for accessing useful furo[2, 3- b ]pyrrole and thieno[2, 3- b ]pyrrole libraries. Graphical abstract: