Surgical management of leukoderma after burn: A review. Issue 2 (March 2018)

• Record Type: Journal Article
• Authors: Maranda, Eric L.; Wang, Mindy X.; Shareef, Shahjahan; Tompkins, Bryon A.; Emerson, Christopher; Badiavas, Evangelos V.
• Is Part Of: Burns. Volume 44:Issue 2(2018)
• Page Start: 256
• Page End: 262
• Publication Date: 2018-03
• Subjects: Burns and scalds -- Periodicals; 617.11
• DOI: 10.1016/j.burns.2017.05.004
• Languages: English
• ISSNs: 0305-4179

Abstract

Highlights: Comparing studies of various surgical techniques to treat leukoderma after burn. Punch minigrafting & noncultured keratinocyte suspension methods showed the most improvement. Cultured autograft, cell suspension spray and chip skin grafting methods have great potential. A combination of a highly effective low cost method with a limited side effect profile is desired. Need more studies to determine superiority of surgical methods for leukoderma after burn. Abstract: Burns are a common and sometimes devastating injury causing a significant amount of pain, disability, and occasionally death. Burns can have serious aesthetic and functional consequences such as pigmentary changes and formation of scar tissue. Hypopigmentation or depigmentation is often a result of partial- or full-thickness burns, which is referred to as leukoderma after burn. Thus, this study is aimed at systematically reviewing the surgical options for treating leukoderma after burn in order to gain insight into the advantages, disadvantages, and future implications of each surgical technique. The surgical procedures reviewed include dermabrasion with thin split thickness grafting, epidermal cell suspension spray, suction blister epidermal minigrafting, minigrafting, cultured epithelium, noncultured keratinocyte suspension, and chip skin grafting.