Palladium‐Catalyzed Three‐Component Tandem Reaction for One‐pot Highly Stereoselective Synthesis of (Z)‐α‐Hydroxymethyl Allylic Sulfones. Issue 4 (6th November 2017)

• Record Type: Journal Article
• Authors: Hou, Yunlei; Shen, Qi; Li, Zefei; Chen, Shaowei; Zhao, Yanfang; Qin, Mingze; Gong, Ping
• Is Part Of: Advanced synthesis & catalysis. Volume 360:Issue 4(2018)
• Page Start: 631
• Page End: 636
• Publication Date: 2017-11-06
• Subjects: allylic sulfones -- three-component tandem reaction -- Pd-catalyzed -- sulfonyl hydrazides -- allenes; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201701011
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: A novel method is reported for the stereoselective synthesis of highly functionalized allyl aryl sulfones. This protocol is based on a Pd‐catalyzed three‐component tandem reaction of sulfonyl hydrazides and aryl iodides with allenes and exhibits high ( Z )‐selectivity, good yields, minimal waste, ample product scope, and operational simplicity. Abstract :