N‐Substituted Hydrazones by Manganese‐Catalyzed Coupling of Alcohols with Hydrazine: Borrowing Hydrogen and Acceptorless Dehydrogenation in One System. Issue 8 (29th January 2018)

• Record Type: Journal Article
• Authors: Das, Uttam Kumar; Ben‐David, Yehoshoa; Diskin‐Posner, Yael; Milstein, David
• Is Part Of: Angewandte Chemie international edition. Volume 57:Issue 8(2018)
• Page Start: 2179
• Page End: 2182
• Publication Date: 2018-01-29
• Subjects: dehydrogenation -- hydrazones -- hydrogen borrowing -- manganese -- reaction mechanisms; Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201712593
• Languages: English
• ISSNs: 1433-7851

Abstract

Abstract: An unprecedented one‐step synthesis of N‐substituted hydrazones by coupling of alcohols with hydrazine is reported. This partial hydrogen‐borrowing reaction is catalyzed by a new manganese pincer complex under mild reaction conditions, thus liberating water and dihydrogen as the only byproducts. Mechanistic insight, based on the observation of intermediates, is provided. Abstract : In the zone : An unprecedented one‐step synthesis of N‐substituted hydrazones by coupling of alcohols with hydrazine is reported. This partial hydrogen‐borrowing and acceptorless dehydrogenation reaction is catalyzed by a new manganese pincer complex under mild reaction conditions, and liberates water and dihydrogen as the only byproducts.