Nickel/Zinc Iodide Co‐catalytic Asymmetric [2+2] Cycloaddition Reactions of Azabenzonorbornadienes with Terminal Alkynes. Issue 3 (23rd November 2017)

• Record Type: Journal Article
• Authors: Chen, Jingchao; Xu, Xin; He, Zhenxiu; Qin, Hongyu; Sun, Weiqing; Fan, Baomin
• Is Part Of: Advanced synthesis & catalysis. Volume 360:Issue 3(2018)
• Page Start: 427
• Page End: 431
• Publication Date: 2017-11-23
• Subjects: nickel -- zinc -- cycloaddition -- alkyne -- azabenzonorbornadiene; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201701133
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: The asymmetric [2+2] cycloaddition reactions of alkenes with alkynes are interesting as it has provided a powerful method for the construction of fused and strained cyclobutenes with multiple chiral centers. In this paper, we report the establishment of a dual catalysts system comprising nickel and zinc, which allowed the asymmetric [2+2] cycloaddition reactions of azabenzonorbornadienes with terminal alkynes in good yields and excellent enantioselectivities. Abstract :