A cluster of scedosporiosis in lung transplant candidates and recipients: The Zurich experience and review of the literature. Issue 1 (27th November 2017)

• Record Type: Journal Article
• Authors: Abela, Irene A.; Murer, Christian; Schuurmans, Macé M.; Schmitt, Juergen W.; Muller, Frabci; Imkamp, Frank; Mueller, Nicolas J.; Benden, Christian
• Is Part Of: Transplant infectious disease. Volume 20:Issue 1(2018)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2017-11-27
• Subjects: cystic fibrosis -- lung transplantation -- scedosporiosis -- Scedosporium; Transplantation of organs, tissues, etc -- Complications -- Periodicals; Communicable diseases -- Periodicals; Infection -- Periodicals; 617.01
• DOI: 10.1111/tid.12792
• Languages: English
• ISSNs: 1398-2273

Abstract

Abstract: Scedosporium species are fungal pathogens increasingly recognized in cystic fibrosis (CF). They can cause multiresistant, life‐threatening infections that are of particular concern in CF patients undergoing lung transplantation, as optimal treatment remains unclear. Here, we describe our Zurich experience of CF patients with Scedosporium infection. Disseminated infection occurred in one patient after transplantation and was successfully treated. We propose a step‐by‐step approach to treat candidates with colonization, and discuss our cases in the context of the current literature.