Specific labeling of mitochondria of Chlamydomonas with cationic helicene fluorophores. Issue 6 (15th January 2018)

• Record Type: Journal Article
• Authors: Bauer, Christoph; Duwald, Romain; Labrador, Geraldine Maria; Pascal, Simon; Moneva Lorente, Pau; Bosson, Johann; Lacour, Jérôme; Rochaix, Jean-David
• Is Part Of: Organic & biomolecular chemistry. Volume 16:Issue 6(2018)
• Page Start: 919
• Page End: 923
• Publication Date: 2018-01-15
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c7ob02906c
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : Twelve cationic helicenes and one triangulene were tested for the specific labeling of mitochondria from algal cells. Abstract : Twelve cationic helicenes and one triangulene were tested for the specific labeling of mitochondria from algal cells. Octyl ester derivative5 readily penetrates algal cells and gives rise to clear fluorescence patterns when it is used at concentrations in the μM range. Under these conditions, cell structures are well preserved and cell survival is not compromised. Cationic helicene compounds such as5 provide new useful tools for examining the mitochondrial network and its dynamics including fission and fusion events.