Syphilis masquerading as focal segmental glomerulosclerosis. (June 2014)

• Record Type: Journal Article
• Authors: Hartley, AJ; Rajakariar, R; Sheaff, M; Buckland, M; Goh, B; O'Connell, R
• Is Part Of: International journal of STD & AIDS. Volume 25:Number 7(2014:Jul.)
• Page Start: 529
• Page End: 531
• Publication Date: 2014-06
• Subjects: Sexually transmitted infections -- syphilis -- late -- Treponema pallidum -- focal segmental glomerulosclerosis -- glomerulonephritis -- doxycycline -- nephrotic -- renal -- proteinuria; Sexually transmitted diseases -- Periodicals; AIDS (Disease) -- Periodicals; 616.951
• DOI: 10.1177/0956462413516940
• Languages: English
• ISSNs: 0956-4624

Abstract

A patient referred to the genitourinary clinic for positive syphilis serology was found to have symptoms and signs of nephrotic syndrome. A renal biopsy showed focal segmental glomerulosclerosis (FSGS). Doxycycline 200 mg twice daily for 28 days coincided with considerable decrease in proteinuria and rise in serum albumin, suggesting a causal relationship.