Acneiform eruptions caused by vitamin B12: A report of five cases and review of the literature. (8th June 2017)

• Record Type: Journal Article
• Authors: Veraldi, Stefano; Benardon, Susanna; Diani, Marco; Barbareschi, Mauro
• Is Part Of: Journal of cosmetic dermatology. Volume 17:Number 1(2018:Feb.)
• Page Start: 112
• Page End: 115
• Publication Date: 2017-06-08
• Subjects: acne -- acneiform eruptions -- vitamin B12; Skin -- Diseases -- Treatment -- Periodicals; Lasers in surgery -- Periodicals; Skin -- Pathophysiology -- Periodicals; Surgery, Plastic -- Periodicals; 616.5
• DOI: 10.1111/jocd.12360
• Languages: English
• ISSNs: 1473-2130

Abstract

Summary: We describe five cases of acneiform eruption caused by vitamin B12 in five females aged 37, 32, 62, 29, and 21 years, respectively. The eruption appeared from 1 week to 5 months after the beginning of the therapy with i.m. or oral vitamin B12. Clinical picture was characterized by papules and pustules located on the face. In three patients, similar lesions were also present on the neck, shoulders, chest, and upper portion of the back. Comedones and cysts were absent. In two patients, serum vitamin B12 levels were very high. Histopathologic examination in one patient revealed an eosinophilic folliculitis. Spontaneous and complete remission was observed in all patients 3‐6 weeks after vitamin B12 discontinuation.