Esophageal atresia and Beckwith–Wiedemann syndrome in one of the naturally conceived discordant newborn twins: first report. Issue 2 (13th January 2018)

• Record Type: Journal Article
• Authors: Serra, Gregorio; Antona, Vincenzo; Schierz, Mandy; Vecchio, Davide; Piro, Ettore; Corsello, Giovanni
• Is Part Of: Clinical case reports. Volume 6:Issue 2(2018)
• Page Start: 399
• Page End: 401
• Publication Date: 2018-01-13
• Subjects: Assisted reproductive techniques -- buccal swab -- hypomethylation -- KCNQ1OT1 gene -- phenotypical discordance; Medicine -- Periodicals; 616.09
• DOI: 10.1002/ccr3.1103
• Languages: English
• ISSNs: 2050-0904

Abstract

Key Clinical Message: Recent studies report a high incidence of monozygotic twinning in Beckwith–Wiedemann syndrome. A phenotypical discordance in monozygotic twins is rare. Twinning and Beckwith–Wiedemann syndrome show higher incidence in children born after assisted reproductive techniques. We report on the first observation of esophageal atresia and Beckwith–Wiedemann syndrome in one of the naturally conceived discordant monozygotic twins. Abstract : Recent studies report a high incidence of monozygotic twinning in Beckwith–Wiedemann syndrome. A phenotypical discordance in monozygotic twins is rare. Twinning and Beckwith–Wiedemann syndrome show higher incidence in children born after assisted reproductive techniques. We report on the first observation of esophageal atresia and Beckwith–Wiedemann syndrome in one of the naturally conceived discordant monozygotic twins.