State of the art review: Chemotherapy‐induced cardiotoxicity in children. (11th December 2017)

• Record Type: Journal Article
• Authors: Loar, Robert W.; Noel, Cory V.; Tunuguntla, Hari; Colquitt, John L.; Pignatelli, Ricardo H.
• Is Part Of: Congenital heart disease. Volume 13:Number 1(2018)
• Page Start: 5
• Page End: 15
• Publication Date: 2017-12-11
• Subjects: anthracyclines -- cardiotoxicity -- chemotherapy -- congestive heart failure -- pediatrics; Congenital heart disease -- Periodicals; 616.1204305
• DOI: 10.1111/chd.12564
• Languages: English
• ISSNs: 1747-079X

Abstract

Abstract: Chemotherapy‐induced cardiotoxicity in adults and children is a topic with a growing interest in the cardiology literature. The ability to detect cardiac dysfunction in a timely manner is essential in order to begin adequate treatment and prevent further deterioration. This article aims to provide a review on the myocardial injury process, chemotherapeutic agents that lead to cardiotoxicity, the definition of cardiotoxicity, and the methods of timely detection and treatment.