Relative pressure estimation from velocity measurements in blood flows: State‐of‐the‐art and new approaches. (9th November 2017)

• Record Type: Journal Article
• Authors: Bertoglio, Cristóbal; Nuñez, Rodolfo; Galarce, Felipe; Nordsletten, David; Osses, Axel
• Is Part Of: International journal for numerical methods in biomedical engineering. Volume 34:Number 2(2018)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2017-11-09
• Subjects: blood flows -- Navier‐Stokes equations -- phase‐contrast MRI -- relative pressure estimation; Biomedical engineering -- Periodicals; Imaging systems in medicine -- Periodicals; Numerical analysis -- Periodicals; Engineering mathematics -- Periodicals; 610.28
• DOI: 10.1002/cnm.2925
• Languages: English
• ISSNs: 2040-7939

Abstract

Abstract: The relative pressure difference across stenotic blood vessels serves as an important clinical index for the diagnosis of many cardiovascular diseases. While the clinical gold standard for relative pressure difference measurements is invasive catheterization, Phase‐Contrast Magnetic Resonance Imaging has emerged as a promising tool for enabling a noninvasive quantification, by linking highly spatially resolved velocity measurements with relative pressures via the incompressible Navier‐Stokes equations. In this work, we provide a review and analysis of current methods for relative pressure estimation and propose 3 additional techniques. Methods are compared using synthetic data from numerical examples, and sensitivity to subsampling and noise was explored. Through our analysis, we verify that the newly proposed approaches are more robust with respect to spatial subsampling and less sensitive to noise and therefore provide improved means for estimating relative pressure differences noninvasively. Abstract : We review, analyse and compare state‐of‐the‐art relative pressure estimation methods from full field velocity measurements. We also propose modifications of some of the methods, which result in improved estimations compared with the state‐of‐the‐art approaches.