Alkylative kinetic resolution of vicinal diols under phase-transfer conditions: a chiral ammonium borinate catalysis. Issue 5 (19th December 2017) - Pawliczek, Martin
Abstract : Alkylative kinetic resolution of vicinal alcohols is realized by a cooperative chiral ammonium borinate catalysis. Abstract : Herein, we report the first alkylative kinetic resolution of vicinal alcohols realized by cooperative use of a chiral quaternary ammonium salt and an achiral borinic acid. In addition, a catalytic regioselective alkylation of a secondary alcohol in the presence of an unprotected primary one is presented, emphasizing the unique selectivity and potential of this ammonium borinate catalysis.