An electrochemical oxidative homo-coupling reaction of imidazopyridine heterocycles to biheteroaryls. Issue 3 (16th January 2018)

• Record Type: Journal Article
• Authors: Gao, Yongyuan; Wang, Yang; Zhou, Jie; Mei, Haibo; Han, Jianlin
• Is Part Of: Green chemistry. Volume 20:Issue 3(2018)
• Page Start: 583
• Page End: 587
• Publication Date: 2018-01-16
• Subjects: Environmental chemistry -- Industrial applications -- Periodicals; Environmental management -- Periodicals; 660
• DOI: 10.1039/c7gc03563b
• Languages: English
• ISSNs: 1463-9262

Abstract

Abstract : An electrochemical homo-coupling reaction of imidazopyridine heterocycles has been developed for the synthesis of biheteroaryls. This reaction features good compatibility, high yields and excellent regioselectivities, which provides an efficient access to biheteroaryl compounds. Abstract : An electrochemical dehydrogenative homo-coupling reaction of imidazopyridine-based heterocycles has been developed, which affords biheteroaryls with good chemical yields and high regioselectivities. This reaction is conducted in a simple undivided cell at room temperature, which avoids the use of any metal-catalysts, additives and oxidants. This reaction tolerates a wide scope of substrates, which provides an easy and green strategy for the preparation of important bioactive biheteroaryl compounds.