An elimination/Heck coupling/allylation cascade reaction: synthesis of 2, 3-dihydrobenzofurans from allenoate adducts. Issue 10 (16th January 2018)

• Record Type: Journal Article
• Authors: Yang, Jianguo; Mo, Hanjie; Wu, Haijian; Cao, Dongdong; Pan, Chengmin; Wang, Zhiming
• Is Part Of: Chemical communications. Volume 54:Issue 10(2018)
• Page Start: 1213
• Page End: 1216
• Publication Date: 2018-01-16
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c7cc07435b
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : A highly regio- and stereoselective Pd-catalyzed cascade reaction of allenoate adducts has been developed. Abstract : A highly regio- and stereoselective Pd-catalyzed cascade reaction of allenoate adducts has been developed. Various allenoate adducts of phosphine-catalyzed addition of allenoates are found to be efficient substrates for the preparation of 2, 3-dihydrobenzofuran. It is the first example of allenoate adducts used as ideal and practical precursors of hard-to-get functionalized 1, 3-butadienes for heterocycle synthesis.