Surgical revascularization of the celiac artery for persistent intestinal ischemia in short bowel syndrome. (January 2018)

• Record Type: Journal Article
• Authors: Roussel, Arnaud; Nuzzo, Alexandre; Pellenc, Quentin; Castier, Yves; De Blic, Romain; Cerceau, Pierre; Boulitrop, Célia; Coblence, Mathieu; Aguir, Sonia; Mordant, Pierre; Maggiori, Léon; Huguet, Audrey; Sibert, Annie; Joly, Francisca; Corcos, Olivier
• Is Part Of: International journal of surgery. Volume 49(2018)
• Page Start: 39
• Page End: 44
• Publication Date: 2018-01
• Subjects: Celiac artery -- Acute mesenteric ischemia -- Short bowel syndrome -- Parenteral nutrition -- Digestive rehabilitation; AMI acute mesenteric ischemia -- IMA inferior mesenteric artery -- PII persistent intestinal ischemia -- PN parenteral nutrition -- SBS short bowel syndrome -- SMA superior mesenteric artery; Surgery -- Periodicals; Surgical Procedures, Operative -- Periodicals; 617.005
• DOI: 10.1016/j.ijsu.2017.12.010
• Languages: English
• ISSNs: 1743-9191

Abstract

Abstract: Background and objectives: Without prompt superior mesenteric artery (SMA) revascularization, acute mesenteric ischemia (AMI) frequently leads to death or short bowel syndrome (SBS). In SBS patients, persistent or chronic intestinal ischemia (PII) of the remnant bowel can lead to recurrences of AMI. Since SMA revascularization is sometimes unfeasible, celiac artery (CA) revascularization may improve blood supply to the remnant bowel. The aim of this study was to describe and to assess our experience of the CA revascularization in case of SMA occlusion unsuitable for revascularization in the setting of PII in SBS patients. Methods: All consecutive patients with i) SBS consecutive to AMI, ii) persistent intestinal ischemia (PII), iii) irreversible SMA occlusion, i.e unsuitable for radiological or surgical revascularization and iv) occlusion or severe stenosis of the CA were included. Results: Thirteen patients (7 males/6 females, mean age = 47.2 ± 12.1 years) were included. The mean length of remnant small bowel was 47 ± 39 cm and 77% of patients had a stoma. The types of revascularization included anterograde aorto-hepatic bypass n = 11 (84%), ilio-hepatic bypass n = 1 (8%) and endarterectomy n = 1 (8%). Major adverse events were observed in 5 cases: bypass graft infection (n = 2), hemorrhagic pericarditis (n = 2), hemorrhagic shock (n = 2) and aortic false aneurysm (n = 1). After a mean follow-up of 27.0 ± 25.2 months, symptoms of PII relieved in 12 cases (92%) allowing for digestive surgical rehabilitation with continuity restoration in 7 patients (54%). PN was weaned for 2 patients. One-year and 3-year survival rates were 73.8% and 73.8% respectively. No recurrence of AMI or further need for bowel resection was noticed. Conclusion: For patients with SBS suffering from PII with CA occlusion or stenosis without possibility of SMA revascularization, the surgical revascularization of the CA allowed digestive rehabilitation with acceptable morbidity and mortality rates. Highlights: Unattainable revascularization of the superior mesenteric artery leads to short bowel syndrome. Persistent ischemia may compromise digestive rehabilitation and long-term survival. Surgical revascularization of the celiac artery may improve digestive and survival outcomes.