Cartilage: Biomimetic Study of the Extracellular Matrix. Issue 1622 (2014)

• Record Type: Journal Article
• Authors: Anyaeji, Chinedu I.; Basser, Peter J.; Horkay, Ferenc
• Is Part Of: MRS proceedings. Issue 1622:(2014)
• Page Start: 61
• Page End: 68
• Publication Date: 2014
• Subjects: biomimetic (assembly), -- elastic properties, -- tissue; Electrical engineering -- Congresses; Physics -- Congresses; Materials -- Research -- Congresses; Materials science -- Congresses; 620.11
• DOI: 10.1557/opl.2014.55
• Languages: English
• ISSNs: 0272-9172

Abstract

ABSTRACT: Cartilage is a complex biological tissue that exhibits gel-like behavior. Its primary biological function is providing compressive resistance to external loading and nearly frictionless lubrication of joints. In this study, we model cartilage extracellular matrix using a biomimetic system. We demonstrate that poly(vinyl) alcohol (PVA) hydrogels are robust biomaterials exhibiting mechanical and swelling properties similar to that of cartilage extracellular matrix. A comparison is made between the macroscopic behavior of PVA gels and literature data reported for cartilage.