Site selectivities in fluorination. Issue 9 (28th February 2018)

• Record Type: Journal Article
• Authors: Ishida, Syo; Sheppard, Tom; Nishikata, Takashi
• Is Part Of: Tetrahedron letters. Volume 59:Issue 9(2018)
• Page Start: 789
• Page End: 798
• Publication Date: 2018-02-28
• Subjects: Fluorination -- Site-selective -- Catalyst; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2018.01.044
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Highlights: Recent digests on site-selective fluorinations. Fluorination of alcohols, alkyl halides and CH bonds. Overview of each selective fluorination reactions including catalytic reaction. Abstract: In the synthesis of bio-active compounds, fluorinated compounds play a prominent role. However, the site-selective fluorination of organic molecules is often challenging, because activation of a reaction site using a fluorinating reagent can be difficult in a substrate possessing many functional groups. This digest introduces recent examples of site-selective fluorination reactions.