Front Cover: Tunable Performance of Manganese Oxide Nanostructures as MRI Contrast Agents (Chem. Eur. J. 6/2018). Issue 6 (19th December 2017)

• Record Type: Journal Article
• Authors: Bañobre‐López, Manuel; García‐Hevia, Lorena; Cerqueira, M. Fatima; Rivadulla, Francisco; Gallo, Juan
• Is Part Of: Chemistry. Volume 24:Issue 6(2018)
• Page Start: 1217
• Page End: 1217
• Publication Date: 2017-12-19
• Subjects: electron spin resonance spectroscopy -- imaging agents -- magnetic resonance imaging -- manganese dioxide -- nanostructures; Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201705893
• Languages: English
• ISSNs: 0947-6539

Abstract

Abstract : A simple one‐pot method was used to prepare a range of manganese oxide nanostructures of different nature (MnO, MnO2, Mn3 O4 ) and shape, to be explored as MRI contrast agents. The availability of redox states of Mn required a special combination of techniques to unequivocally identify the phase of the materials. From the imaging point of view, while MnO nanostructures behave as classic T 1 contrast enhancers, MnO2 nanourchins emerge as efficient responsive probes, superior to MnO2 nanosheets, able to increase their signal over 140‐fold upon activation under oncology‐relevant conditions. More information can be found in the Full Paper by M. Bañobre‐López, J. Gallo et al. onpage 1295 .