Crack the state of silence: Tune the depth of cellular quiescence for cancer therapy. (2nd January 2018)
- Record Type:
- Journal Article
- Title:
- Crack the state of silence: Tune the depth of cellular quiescence for cancer therapy. (2nd January 2018)
- Main Title:
- Crack the state of silence: Tune the depth of cellular quiescence for cancer therapy
- Authors:
- Fujimaki, Kotaro
Yao, Guang - Abstract:
- ABSTRACT: The regulation of cellular quiescence underlies numerous physiopathological phenomena. We recently found that quiescence depth can be tuned as to adjust a dimmer switch, by altering the expression of genes in the Retinoblastoma (Rb)-E2f pathway. Reducing quiescence depth may wake dormant cancer cells and make them susceptible to treatment.
- Is Part Of:
- Molecular & cellular oncology. Volume 5:Number 1(2018)
- Journal:
- Molecular & cellular oncology
- Issue:
- Volume 5:Number 1(2018)
- Issue Display:
- Volume 5, Issue 1 (2018)
- Year:
- 2018
- Volume:
- 5
- Issue:
- 1
- Issue Sort Value:
- 2018-0005-0001-0000
- Page Start:
- Page End:
- Publication Date:
- 2018-01-02
- Subjects:
- cellular quiescence -- quiescence depth -- cell cycle entry -- Rb-E2F pathway
Tumors -- Periodicals
Neoplasms
Periodicals
616.99 - Journal URLs:
- http://www.tandfonline.com/loi/kmco20#.VyIIeFL2aic ↗
http://www.tandfonline.com/ ↗ - DOI:
- 10.1080/23723556.2017.1403531 ↗
- Languages:
- English
- ISSNs:
- 2372-3556
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 5719.xml