A mild method for synthesizing carboxylic acids by oxidation of aldoximes using hypervalent iodine reagents. Issue 4 (9th January 2018)

• Record Type: Journal Article
• Authors: Nakamura, Akira; Kanou, Hodaka; Tanaka, Junki; Imamiya, Akira; Maegawa, Tomohiro; Miki, Yasuyoshi
• Is Part Of: Organic & biomolecular chemistry. Volume 16:Issue 4(2017)
• Page Start: 541
• Page End: 544
• Publication Date: 2018-01-09
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c7ob02858j
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : A variety of aldoximes can be efficiently converted into the corresponding carboxylic acids with hypervalent iodine reagent. Abstract : A mild oxidation method for the conversion of aldoximes to carboxylic acids was developed mediated by hypervalent iodine reagents. This method covers a wide range of functionalized aldoximes and proceeds under mild conditions, utilizing PhI(OH)OTs as an oxidant.