Mn(OAc)3*2H2O promoted addition of arylboronic acids to quinoxalin-2-ones. Issue 7 (14th February 2018)

• Record Type: Journal Article
• Authors: Ramesh, Boora; Reddy, C. Ravikumar; Kumar, G. Ravi; Reddy, B.V. Subba
• Is Part Of: Tetrahedron letters. Volume 59:Issue 7(2018)
• Page Start: 628
• Page End: 631
• Publication Date: 2018-02-14
• Subjects: Aryl boronic acids -- Arylation -- Quinoxalin-2-ones -- SET reactions; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2017.12.085
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Highlights: This is the first report using Mn(OAc)3 . Describes the addition of aryl boronic acids to cyclic imines. This method is cost effective and operationally simple. It is compatible with various functional groups. This method works with a diverse range of substrates. Abstract: A simple method has been developed for the synthesis of 3-aryl quinoxalin-2-one derivatives through an oxidative cross-coupling of arylboronic acids with quinoxalin-2-ones using a readily available oxidant Mn(III) acetate dihydrate. This method provides 3-aryl quinoxalin-2-one scaffolds with a broad substrate scope.