Synthesis of the sedum and related alkaloids: A personal perspective. Issue 7 (14th February 2018)

• Record Type: Journal Article
• Authors: Bates, Roderick W.
• Is Part Of: Tetrahedron letters. Volume 59:Issue 7(2018)
• Page Start: 559
• Page End: 567
• Publication Date: 2018-02-14
• Subjects: BIPHEPHOS 6, 6′-[(3, 3′-Di-tert-butyl-5, 5′-dimethoxy-1, 1′-biphenyl-2, 2′-diyl)bis(oxy)]bis(dibenzo[d, f][1, 3, 2]dioxaphosphepin) -- CDI carbonyl diimidazole -- DIAD di-isopropylazodicarboxylate -- DEAD diethylazodicarboxylate -- DMA N, N-dimethylacetamide -- IBX 2-idoxybenzoic acid -- mcpba m-chloroperbenzoic acid -- Me-CBS 2-methyl-CBS oxaborolidine -- Phth phthaloyl -- PMB p-methoxybenzyl -- PPTS pyridinium p-toluenesulfonate -- PS-PPTS polymer supported pyridinium p-toluenesulfonate -- p-TsOH p-toluenesulfonic acid -- TMG tetramethyl guanidine; Alkaloids -- Synthesis -- Sedum; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2017.12.026
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Highlights: Synthesis of the sedum and related alkaloids. Recent significant developments. Inventive contributions to the field. Abstract: Significant recent contributions to the synthesis of the sedum alkaloids are discussed. Related compounds, such as pinidinol, porantheridine, dumetorine and the tetraponerines are also included. The syntheses are categorised according to the key motif or chemistry employed: isoxazolidines, metathesis, asymmetric aza-Michael, heterocycle lithiation, organocatalysis, aromatic heterocycles and chiral imines.