Bulk Synthesis of Monodisperse and Highly Biocompatible Poly(ɛ-caprolactone)-diol by Transesterification Side-Reactions. Issue 6 (13th April 2018)

• Record Type: Journal Article
• Authors: Shahrousvand, Mohsen; Mir Mohamad Sadeghi, Gity; Salimi, Ali; Nourany, Mohammad
• Is Part Of: Polymer-plastics technology and engineering. Volume 57:Issue 6(2018)
• Page Start: 492
• Page End: 499
• Publication Date: 2018-04-13
• Subjects: Biocompatible -- MTT assay -- polycaprolactone diol -- transesterification; Polymers -- Periodicals; Polymerization -- Periodicals; Polymers -- Periodicals; Engineering -- Periodicals; Plastics -- Periodicals; 668.9
• DOI: 10.1080/03602559.2016.1211690
• Languages: English
• ISSNs: 0360-2559

Abstract

ABSTRACT: Ring-opening polymerization of ε-caprolactone was performed at 130°C, under partial vacuum in the presence of stannous octoate as the catalyst and 1, 4-butanediol as the initiator. After the termination of polymerization by deionized water, a hydroxyl group formed at the end of the polymer chains. Structure of the synthetic poly(ε-caprolactone)-diols (PCL-diol), molecular weight, polydispersity index, and Cell viability were evaluated. Very narrow distribution in the molecular weight obtained for PCL-diols is due to a new method for synthesis. It was shown that by the increase in PCL-diols, the compatibility of human mesenchymal stem cells grew up. GRAPHICAL ABSTRACT: