Tp–e interval and Tp–e/QT ratio in patients with Human Immunodeficiency Virus. Issue 1 (January 2018)

• Record Type: Journal Article
• Authors: Ünal, Sefa; Yayla, Çağrı; Açar, Burak; Ertem, Ahmet G.; Akboğa, Mehmet K.; Gökaslan, Serkan; Erdöl, Mehmet A.; Sönmezer, Meliha Ç.; Kaya Kiliç, Esra; Ataman Hatipoğlu, Çiğdem; Tulek, Necla; Erdinç, Fatma S.; Aydoğdu, Sinan; Temizhan, Ahmet
• Is Part Of: Journal of infection and public health. Volume 11:Issue 1(2018)
• Page Start: 35
• Page End: 38
• Publication Date: 2018-01
• Subjects: Human Immunodeficiency Virus -- Tp–e interval -- Tp–e/QT ratio; Communicable diseases -- Periodicals; Public health -- Periodicals; Epidemiology -- Periodicals; Nosocomial infections -- Prevention -- Periodicals; Medical microbiology -- Periodicals; 614.4
• DOI: 10.1016/j.jiph.2017.02.008
• Languages: English
• ISSNs: 1876-0341

Abstract

Abstract: Human Immunodeficiency Virus (HIV) infection and AIDS are known to cause cardiovascular diseases such as premature coronary artery disease, cardiomyopathy, and arrhythmias. Recently, Tp–e interval and Tp–e/QT ratio has been shown as a novel marker of ventricular repolarization. We aimed to evaluate the ventricular repolarization using Tp–e interval and Tp–e/QT ratio in patients with Human Immunodeficiency Virus (HIV) infection. Totally 48 patients with HIV and 60 control subjects were enrolled to the study. Tp–e interval, Tp–e/QT and Tp–e/QTc ratio were measured from the 12-lead electrocardiogram. Tp–e interval, Tp–e/QT ratio and Tp–e/QTc ratio were significantly higher in patients with HIV than control subjects (all p < 0.01). In correlation analysis, there were positive correlation between Tp–e interval and disease duration (r = 0.298, p = 0.048). and inverse correlation between Tp–e interval and CD4 count(r = −0.303, p = 0.036). Our study showed that Tp–e interval, Tp–e/QT and Tp–e/QTc ratios were increased in patients with HIV than control subjects.