Achieving antimicrobial activity through poly(N-methylvinylimidazolium) iodide brushes on binary-grafted polypropylene suture threads. (2nd November 2017)

• Record Type: Journal Article
• Authors: López-Saucedo, F.; Flores-Rojas, G.G.; Bucio, E.; Alvarez-Lorenzo, C.; Concheiro, A.; González-Antonio, O.
• Is Part Of: MRS communications. Volume 7:Number 4(2017)
• Page Start: 938
• Page End: 946
• Publication Date: 2017-11-02
• Subjects: Materials -- Periodicals; 620.11
• DOI: 10.1557/mrc.2017.121
• Languages: English
• ISSNs: 2159-6859

Abstract

Abstract: Abstract : Harnessing the properties of imidazolium species, antimicrobial activity against Gram-negative and Gram-positive bacteria was attained by binary-grafting 2-hydroxyethyl methacrylate (HEMA) or N -isopropylacrylamide, followed by N -vinylimidazole onto polypropylene (PP) monofilaments (sutures) using 60 Co γ -rays. Ulterior functionalization with methyl iodide was carried out to endow brushes with antimicrobial activity on the PP surface. The PP-grafted sutures were characterized by means of Fourier-transform infrared spectroscopy attenuated total reflection, scanning electron microscopy, differential scanning calorimetry, and thermogravimetric analysis, and regarding the mechanical properties and the responsiveness to pH and temperature. Tests were performed on Escherichia coli and Staphylococcus aureus achieving large inhibition zones.