Amphiphilic diblock copolymer of hydrophilic-functionalized lactone and lactide via switchable organocatalytic polymerization. Issue 4 (9th January 2018)

• Record Type: Journal Article
• Authors: Bai, Jinmei; Tang, Xiaoying; Zhang, Yuan; Lin, Jingjing; Li, Minfeng
• Is Part Of: RSC advances. Volume 8:Issue 4(2018)
• Page Start: 1905
• Page End: 1908
• Publication Date: 2018-01-09
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c7ra12843f
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : Main-chain degradable amphiphilic diblock copolymers prepared by one-pot ring-opening polymerization via actively manipulating catalytic states of an acid–base catalytic system were capable of forming stable micelle with optimal particle size. Abstract : Main-chain degradable amphiphilic diblock copolymers composed of a hydrophilic-functionalized polyester and PLA were facilely prepared by one-pot ring-opening polymerization (ROP) via actively manipulating the catalytic states of an acid–base catalytic system. The resultant block copolymers showed low critical micelle concentration (CMC) in water and were capable of forming stable micelles with optimal hydrodynamic particle size (average diameter 83 nm) and narrow particle distribution.