A nationwide assessment of outcomes after bile duct reconstruction. Issue 9 (September 2015)

• Record Type: Journal Article
• Authors: Eskander, Mariam F.; Bliss, Lindsay A.; Yousafzai, Osman K.; de Geus, Susanna W.L.; Ng, Sing Chau; Callery, Mark P.; Kent, Tara S.; James Moser, A.; Khwaja, Khalid; Tseng, Jennifer F.
• Is Part Of: HPB. Volume 17:Issue 9(2015:Sep.)
• Page Start: 753
• Page End: 762
• Publication Date: 2015-09
• Subjects: Liver -- Diseases -- Periodicals; Biliary tract -- Diseases -- Periodicals; Pancreas -- Diseases -- Periodicals; 616.362005
• DOI: 10.1111/hpb.12436
• Languages: English
• ISSNs: 1365-182X

Abstract

Abstract: Background: Bile duct reconstruction (BDR) is used to manage benign and malignant neoplasms, congenital anomalies, bile duct injuries and other non-malignant diseases. BDR outcomes overall, by year, and by indication were compared. Methods: Retrospective analysis of Nationwide Inpatient Sample discharges (2004–2011) including ICD-9 codes for BDR. All statistical testing was performed using survey weighting. Univariate analysis of admission characteristics by chi square testing. Multivariate modelling for inpatient complications and inpatient death by logistic regression. Results: Identified 67 160 weighted patient admissions: 2.5% congenital anomaly, 37.4% malignant neoplasm, 2.3% benign neoplasm, 9.9% biliary injury, 47.9% other non-malignant disease. Most BDRs were performed in teaching hospitals (69.6%) but only 25% at centres with a BDR volume more than 35/year. 32.3% involved ≥ 1 complication, and 84.7% were discharges home. There was a 4.2% inpatient death rate. The complication rate increased but the inpatient death rate decreased over time. The rates of acute renal failure increased. Significant multivariate predictors of inpatient death include indication of biliary injury or malignancy, and predictors of any complication include public insurance and non-elective admission. Conclusion: This is the first national description of BDRs using a large database. In this diverse sampling, both procedure indication and patient characteristics influence morbidity and mortality.