A permutation Lempel-Ziv complexity measure for EEG analysis. (May 2015)

• Record Type: Journal Article
• Authors: Bai, Yang; Liang, Zhenhu; Li, Xiaoli
• Is Part Of: Biomedical signal processing and control. Volume 19(2015)
• Page Start: 102
• Page End: 114
• Publication Date: 2015-05
• Subjects: Electroencephalography -- Permutation -- Lempel-Ziv complexity -- Anesthesia -- Epileptic seizure; Signal processing -- Periodicals; Biomedical engineering -- Periodicals; Signal Processing, Computer-Assisted -- Periodicals; Image Processing, Computer-Assisted -- Periodicals; Biomedical Engineering -- Periodicals; 610.28
• DOI: 10.1016/j.bspc.2015.04.002
• Languages: English
• ISSNs: 1746-8094

Abstract

Highlights: A complexity measure for EEG signal analysis is proposed which combines permutation and Lempel-Ziv complexity (PLZC). Robustness of PLZC was tested using a neural mass model, and PLZC was more robust to noise than four classical Lempel-Ziv complexity measures. Application to real EEG data showed that PLZC could better distinguish different anesthesia states and detect epileptic seizures. Abstract: Objective: In this study we develop a new complexity measure of time series by combining ordinal patterns and Lempel-Ziv complexity (LZC) for quantifying the dynamical changes of EEG. Methods: A neural mass model (NMM) was used to simulate EEG data and test the performance of the permutation Lempel-Ziv complexity (PLZC) in tracking the dynamical changes of signals against different white noise levels. Then, the PLZC was applied to real EEG data to investigate whether it was able to detect the different states of anesthesia and epileptic seizures. The Z-score model, two-way ANOVA and t -test were used to estimate the significance of the results. Results: PLZC could successfully track the dynamical changes of EEG series generated by the NMM. Compared with the other four classical LZC based methods, the PLZC was most robust against white noise. In real data analysis, PLZC was effective in differentiating the different anesthesia states and sensitive in detecting epileptic seizures. Conclusions: PLZC is simple, robust and effective for quantifying the dynamical changes of EEG. Significance: We suggest that PLZC is a potential nonlinear method for characterizing the changes in EEG signal.