The Role of Analgesic Adjustment Strategies in Achieving Analgesic Efficacy in Opioid-Tolerant Hospice Patients in China. (May 2014)

• Record Type: Journal Article
• Authors: Deng, Di; Wu, Xin; Fu, Ling; Zhao, Yunxiang; Zhang, Gong; Liang, Chen; Xie, Conghua; Zhou, Yunfeng
• Is Part Of: American journal of hospice & palliative care. Volume 31:Number 3(2014)
• Page Start: 315
• Page End: 321
• Publication Date: 2014-05
• Subjects: diverse strategies -- analgesic -- adjusted -- analgesic efficacy -- opioid tolerance -- hospice patients; Hospice care -- Periodicals; Palliative treatment -- Periodicals; 362.175
• DOI: 10.1177/1049909113494745
• Languages: English
• ISSNs: 1049-9091

Abstract

Diverse strategies of analgesic adjustment are often, respectively, used to sustain analgesic efficiency for opioid-tolerant patients with different refractory factors of pain. In order to select effective analgesic adjustment strategy for hospice patient without knowing explicit causes of diminishing analgesic efficiency, a retrospective data of 743 patients among 3760 hospice patients were analyzed. The efficacy and adverse effects were not significantly different among analgesic adjustment strategies at each adjustment. Opioid duration was not associated with clinical characteristics. For opioid-tolerant hospice patients, the analgesic adjustment strategy can be selected for individual patient. After repeated analgesic adjustments, opioid tapering may also occur.