Sensitive ratiometric detection of Al(iii) ions in a 100% aqueous buffered solution using a fluorescent probe based on a peptide receptor. (4th January 2018)

• Record Type: Journal Article
• Authors: Hwang, Gi Won; Jeon, Jongyong; Neupane, Lok Nath; Lee, Keun-Hyeung
• Is Part Of: New journal of chemistry. Volume 42:Number 2(2018)
• Page Start: 1437
• Page End: 1445
• Publication Date: 2018-01-04
• Subjects: Chemistry -- Periodicals; Chimie -- Périodiques; 540
• DOI: 10.1039/c7nj04160h
• Languages: English
• ISSNs: 1144-0546

Abstract

Abstract : The peptidyl bioprobe detected Al(iii ) ions sensitively in a 100% aqueous buffered solution through ratiometric response. Abstract : Ratiometric detection of Al(iii ) ions in aqueous buffered solutions is still a significant challenge. Herein, a fluorescent probe1 based on a dipeptide receptor bearing a pyrene fluorophore was synthesized by solid phase synthesis for the ratiometric detection of Al(iii ) ions in aqueous solutions. The peptidyl bioprobe detected Al(iii ) ions sensitively in a 100% aqueous buffered solution through ratiometric response. Upon the addition of Al(iii ) ions, the excimer emission at 476 nm increased significantly, and the monomer emission at 395 nm decreased considerably. Approximately 3.5 equiv. of Al(iii ) was required for the complete ratiometric response of1 . Moreover, 1 showed linear responses to nanomolar concentrations (0–500 nM) of Al(iii ) by change in the intensity ratio of the excimer and monomer emissions. The detection limit of1 for Al(iii ) was 138.1 nM ( R 2 = 0.980) in 100% aqueous solutions. The probe showed highly selective response to Al(iii ) in the presence of 16 metal ions. The fluorescent peptidyl probe was suitable for the ratiometric detection of Al(iii ) ions in ground water, tap water, and urine.