A quick, mild and efficient bromination using a CFBSA/KBr system. Issue 93 (20th September 2016)

• Record Type: Journal Article
• Authors: Jiang, Pan-Pan; Yang, Xian-Jin
• Is Part Of: RSC advances. Volume 6:Issue 93(2016)
• Page Start: 90031
• Page End: 90034
• Publication Date: 2016-09-20
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c6ra20217a
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : A quick, mild and efficient oxidative bromination by using CFBSA/KBr system has been developed. It was successfully applied into four different types of compounds including, 1, 3-diketones and β-keto esters, aromatic amines, phenols and heteroarenes. Abstract : Bromination is a fundamental transformation in organic chemistry and brominated compounds as building blocks are of paramount importance in organic synthesis. In our study, we have developed an efficient method of bromination by using a CFBSA/KBr system at room temperature in a short reaction time. Notably, this approach has been proven to be applicable to a range of substrates including 1, 3-diketones and β-keto esters, phenols, aromatic amines and heteroarenes with good to excellent yields.