The electrochemical behaviors of tetrahydropalmatine at a nickel nanoparticles/sulfonated graphene sheets modified glassy carbon electrode. Issue 75 (27th July 2016)

• Record Type: Journal Article
• Authors: Wang, Haihang; Zhai, Haiyun; Chen, Zuanguang; Liang, Zhixian; Wang, Shumei; Zhou, Qing; Pan, Yufang
• Is Part Of: RSC advances. Volume 6:Issue 75(2016)
• Page Start: 71351
• Page End: 71359
• Publication Date: 2016-07-27
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c6ra10667f
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : A novel electrochemical sensor was fabricated to determine THP under optimum conditions, with a considerable repeatability, stability and sensitivity. This method has a similar recovery and RSD compared with HPLC. Abstract : A novel electrochemical sensor was designed to determine tetrahydropalmatine (THP) by using a nickel nanoparticles deposited on sulfonated graphene sheets-modified glassy carbon electrode (NiNPs/SGS/GCE). The components and morphological properties of the NiNPs/SGS nanocomposites were investigated by scanning electron microscopy. The anodic peak current ( I pa ) of THP at the GCE modified with NiNPs/SGS was much higher than those at the bare GCE and SGS/GCE due to the enhanced effect of the modified nanomaterials. Differential pulse voltammetry (DPV) disclosed a good linear relationship between I pa and concentrations of THP (0.50–20.0 μM), with a limit of detection of 0.17 μM. Finally, the modified electrode was successfully applied for the determination of THP in Yuanhu Zhitong capsules.