Presurgical language mapping using event-related high-gamma activity: The Detroit procedure. Issue 1 (January 2018)

• Record Type: Journal Article
• Authors: Kambara, Toshimune; Sood, Sandeep; Alqatan, Zahraa; Klingert, Christine; Ratnam, Diksha; Hayakawa, Akane; Nakai, Yasuo; Luat, Aimee F.; Agarwal, Rajkumar; Rothermel, Robert; Asano, Eishi
• Is Part Of: Clinical neurophysiology. Volume 129:Issue 1(2018:Jan.)
• Page Start: 145
• Page End: 154
• Publication Date: 2018-01
• Subjects: Articulation -- Vocalization -- Auditory and visual perception -- Eloquent areas -- Artifacts -- High-frequency oscillations (HFOs) -- Ripples -- Subdural electroencephalography (EEG) -- Intracranial electrocorticography (ECoG) recording -- Pediatric epilepsy surgery -- Language -- Speech; Neurophysiology -- Periodicals; Electroencephalography -- Periodicals; Electromyography -- Periodicals; Neurology -- Periodicals; 612.8
• DOI: 10.1016/j.clinph.2017.10.018
• Languages: English
• ISSNs: 1388-2457

Abstract

Highlights: We provide video presentations for ECoG-based language mapping. Brain mapping with event-related high-gamma activity has pitfalls to be avoided. We provide standardized auditory stimuli as open-source materials. Abstract: A number of investigators have reported that event-related augmentation of high-gamma activity at 70–110 Hz on electrocorticography (ECoG) can localize functionally-important brain regions in children and adults who undergo epilepsy surgery. The advantages of ECoG-based language mapping over the gold-standard stimulation include: (i) lack of stimulation-induced seizures, (ii) better sensitivity of localization of language areas in young children, and (iii) shorter patient participant time. Despite its potential utility, ECoG-based language mapping is far less commonly practiced than stimulation mapping. Here, we have provided video presentations to explain, point-by-point, our own hardware setting and time–frequency analysis procedures. We also have provided standardized auditory stimuli, in multiple languages, ready to be used for ECoG-based language mapping. Finally, we discussed the technical aspects of ECoG-based mapping, including its pitfalls, to facilitate appropriate interpretation of the data.