Acid-catalyzed reaction of 2-hydroxycyclobutanone with benzylic alcohols. Issue 47 (22nd November 2017)

• Record Type: Journal Article
• Authors: Martis, Alberto; Luridiana, Alberto; Frongia, Angelo; Arca, Massimiliano; Sarais, Giorgia; Aitken, David J.; Guillot, Regis; Secci, Francesco
• Is Part Of: Organic & biomolecular chemistry. Volume 15:Issue 47(2017)
• Page Start: 10053
• Page End: 10063
• Publication Date: 2017-11-22
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c7ob02545a
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : The acid-promoted syntheses of 2-(benzyloxy)cyclobutanones and bis(benzyloxy)dioxatricyclo decanes were achieved starting from 2-hydroxycyclobutanone and variously functionalized benzyl alcohols. Abstract : The acid-promoted syntheses of 2-(benzyloxy)cyclobutanones and bis(benzyloxy)dioxatricyclo decanes were achieved starting from 2-hydroxycyclobutanone and variously functionalized benzyl alcohols. The reaction sequences afforded the desired products in good to high yields and in a solvent-dependent chemoselective fashion.