Nanotechnology in neurosurgery: thinking small, dreaming big. (3rd September 2017)

• Record Type: Journal Article
• Authors: Tan, Aaron; Jeyaraj, Rebecca; Ashkan, Keyoumars
• Is Part Of: British journal of neurosurgery. Volume 31:Number 5(2017)
• Page Start: 538
• Page End: 550
• Publication Date: 2017-09-03
• Subjects: Nanotechnology -- neurosurgery -- molecular imaging -- theranostics -- neuroregeneration; Nervous system -- Surgery -- Periodicals; 617.48
• DOI: 10.1080/02688697.2017.1327017
• Languages: English
• ISSNs: 0268-8697

Abstract

Abstract: Nanotechnology has the power to transform neurosurgery by facilitating intervention at the cellular and subcellular level. The unique properties of nanomaterials will not only improve the management of conditions traditionally treated through neurosurgery, but also make neurosurgical intervention possible for diseases where there are currently limited treatment options. Specifically, nanotechnology appears to be a promising tool for improving molecular imaging, seamlessly integrating diagnosis and therapy in neuro-oncology, identifying targets for selective neuromodulation, as well as promoting neuroregeneration. Despite the vast potential benefits of nanotechnology in neurosurgery, problems related to neurotoxicity and the long-term medical and social consequences must be adequately addressed before nanotechnology becomes a component of surgical care.