A fluorescent activatable probe for imaging intracellular Mg2+  1. Issue 2 (19th December 2017)

• Record Type: Journal Article
• Authors: Treadwell, Ryan; de Moliner, Fabio; Subiros-Funosas, Ramon; Hurd, Toby; Knox, Kirsten; Vendrell, Marc
• Is Part Of: Organic & biomolecular chemistry. Volume 16:Issue 2(2017)
• Page Start: 239
• Page End: 244
• Publication Date: 2017-12-19
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c7ob02965a
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : An BODIPY probe for detection and imaging of Mg 2+ without interference from Ca 2+ is described. Abstract : An activatable BODIPY probe for in vitro detection and fluorescence cell imaging of free Mg 2+ without interference from Ca 2+ is described. Fluorescence amplification of the probe is observed upon detection of physiological concentrations of Mg 2+ due to reduced rotation of the fluorophore and effective chelation by a quinolizine-based core.