A case of suspected MPO‐ANCA‐related hypertrophic pachymeningitis with atypical presentation. (15th September 2017)

• Record Type: Journal Article
• Authors: Koura, Tomoyuki; Kita, Keiichiro; Konishi, Hirofumi
• Is Part Of: Journal of general and family medicine. Volume 18:Number 6(2017)
• Page Start: 409
• Page End: 410
• Publication Date: 2017-09-15
• Subjects: consciousness disorder -- headache -- hypertrophic pachymeningitis -- MPO‐ANCA; Primary care (Medicine) -- Periodicals; Family medicine -- Periodicals; Family Practice; Primary Health Care; Japan; Periodicals; 610
• DOI: 10.1002/jgf2.73
• Languages: English
• ISSNs: 2189-7948

Abstract

Abstract: A 66‐year‐old man presented to our emergency department with acute consciousness disorder, headache, and fever. Initial laboratory data indicated a high level of inflammatory reaction. Enhanced magnetic resonance imaging revealed a thickening of the right cranial dura mater on T1‐weighted images. We presumed the patient was diagnosed as having myeloperoxidase antineutrophil cytoplasmic antibody (MPO‐ANCA)‐related hypertrophic pachymeningitis (HP). Acute impaired consciousness without focal signs is an unusual presentation of HP. This treatable disease should be considered as a differential diagnosis when a patient presents with drowsiness and headache.