Efficient Encapsulation of Fluorinated Drugs in the Confined Space of Water‐Dispersible Fluorous Supraparticles. (23rd November 2017)

• Record Type: Journal Article
• Authors: Pigliacelli, Claudia; Maiolo, Daniele; Nonappa, ; Haataja, Johannes S.; Amenitsch, Heinz; Michelet, Claire; Sánchez Moreno, Paola; Tirotta, Ilaria; Metrangolo, Pierangelo; Baldelli Bombelli, Francesca
• Is Part Of: Angewandte Chemie. Volume 129:Number 51(2017)
• Page Start: 16404
• Page End: 16408
• Publication Date: 2017-11-23
• Subjects: Fluorierte Oberflächen -- Goldnanopartikel -- Hydrophobin -- Selbstorganisation -- Suprapartikel; Chemistry -- Periodicals; 540
• DOI: 10.1002/ange.201710230
• Languages: English
• ISSNs: 0044-8249

Abstract

Abstract: Fluorophobic‐driven assemblies of gold nanomaterials were stabilized into water‐dispersible fluorous supraparticles by the film‐forming protein hydrophobin II. The strategy makes use of fluorous nanomaterials of different dimensions to engineer size and inner functionalization of the resulting confined space. The inner fluorous compartments allow efficient encapsulation and transport of high loadings of partially fluorinated drug molecules in water.