Pattern Recognition: Sequential Double "Clicks" toward Structurally Well‐Defined Heterogeneous N‐Glycoclusters: The Importance of Cluster Heterogeneity on Pattern Recognition In Vivo (Adv. Sci. 2/2017). Issue 2 (February 2017)

• Record Type: Journal Article
• Authors: Latypova, Liliya; Sibgatullina, Regina; Ogura, Akihiro; Fujiki, Katsumasa; Khabibrakhmanova, Alsu; Tahara, Tsuyoshi; Nozaki, Satoshi; Urano, Sayaka; Tsubokura, Kazuki; Onoe, Hirotaka; Watanabe, Yasuyoshi; Kurbangalieva, Almira; Tanaka, Katsunori
• Is Part Of: Advanced science. Volume 4:Issue 2(2017)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2017-02
• Subjects: biodistribution -- heterogeneity -- in vivo kinetics -- N‐glycoalbumin -- noninvasive fluorescence imaging -- pattern recognition; Science -- Periodicals; 505
• DOI: 10.1002/advs.201770006
• Languages: English
• ISSNs: 2198-3844

Abstract

Abstract : In article number 1600394, Almira Kurbangalieva, Katsunori Tanaka, and co‐workers at the RIKEN Biofunctional Synthetic Chemistry Laboratory develop a way to engineer glycan complexes—heterogeneous clusters of sugar chains attached to proteins or lipids—in a way that allows the molecules to be transported preferentially to specific organs of the body through pattern recognition mechanisms, depending on the sugar chains contained in the cluster.