The role of cell-free DNA in predicting colorectal cancer prognosis. (2nd January 2018)

• Record Type: Journal Article
• Authors: Cao, Bo; Zhou, Xin; Yang, Wanli; Ma, Jiaojiao; Zhou, Wei; Fan, Daiming; Hong, Liu
• Is Part Of: Expert review of gastroenterology & hepatology. Volume 12:Number 1(2018)
• Page Start: 39
• Page End: 48
• Publication Date: 2018-01-02
• Subjects: Colorectal cancer -- cell-free DNA -- prognosis -- DNA mutation -- DNA methylation; Gastroenterology -- Periodicals; Liver -- Diseases -- Periodicals; 616.3
• DOI: 10.1080/17474124.2017.1372191
• Languages: English
• ISSNs: 1747-4124

Abstract

ABSTRACT: Introduction : Colorectal cancer is a cancer of the digestive system with poor prognosis. Cell-free DNA has received much attention with its unique predominance, especially in colorectal cancer. Areas covered : This study has summarized recent advancements and challenges regarding cell-free DNA in predicting CRC prognosis. Furthermore, the authors make predictions on the potential developments concerning cell-free DNA in future prognosis prediction techniques. Expert commentary : Cell-free DNA has the value of predicting CRC prognosis as an important biomarke. Further clinical trials should be performed to promote translating cell-free DNA into clinical applications.