What factors are related to recurrent preterm birth among underweight women?*. (4th March 2018)

• Record Type: Journal Article
• Authors: Girsen, Anna I.; Mayo, Jonathan A.; Wallenstein, Matthew B.; Gould, Jeffrey B.; Carmichael, Suzan L.; Stevenson, David K.; Lyell, Deirdre J.; Shaw, Gary M.
• Is Part Of: Journal of maternal-fetal & neonatal medicine. Volume 31:Number 5(2018)
• Page Start: 560
• Page End: 566
• Publication Date: 2018-03-04
• Subjects: Preterm birth -- high-risk pregnancy -- recurrence -- underweight -- body mass index -- inter-pregnancy interval; Obstetrics -- Periodicals; Perinatology -- Periodicals; Infants (Newborn) -- Diseases -- Periodicals; Neonatology -- Periodicals; 618.2
• DOI: 10.1080/14767058.2017.1292243
• Languages: English
• ISSNs: 1476-7058

Abstract

Abstract: Objective: Our objective was to identify factors associated with recurrent preterm birth among underweight women. Methods: Maternally linked hospital and birth certificate records of deliveries in California between 2007 and 2010 were used. Consecutive singleton pregnancies of women with underweight body mass index (BMI <18.5 kg/m 2 ) in the first pregnancy were analyzed. Pregnancies were categorized based on outcome of the first and second birth as: term-term; term-preterm; preterm-term and preterm-preterm. Results: We analyzed 4971 women with underweight BMI in the first pregnancy. Of these, 670 had at least one preterm birth. Among these 670, 86 (21.8%) women experienced a recurrent preterm birth. Odds for first term – second preterm birth were decreased for increases in maternal age (aOR: 0.90, 95%CI: 0.95–0.99) whereas inter-pregnancy interval <6 months was related to both first term – second preterm birth (aOR:1.66, 95%CI: 1.21–2.28) and first preterm birth – second term birth (aOR: 1.43, 95%CI: 1.04–1.96). Factors associated with recurrent preterm birth were: negative or no change in pre-pregnancy weight between pregnancies (aOR: 1.67, 95%CI: 1.07–2.60), inter-pregnancy interval <6 months (aOR: 2.14, 95%CI: 1.29–3.56), and maternal age in the first pregnancy (aOR: 0.93, 95%CI: 0.90–0.97). Conclusions: Recurrent preterm birth among underweight women was associated with younger age, short inter-pregnancy interval, and negative or no weight change between pregnancies.