Comparison of two-risk assessment algorithms for preeclampsia in first trimester with consecutive intake of low-dose aspirin in the high-risk group – an observational study. (4th March 2018)

• Record Type: Journal Article
• Authors: Lakovschek, Ioana-Claudia; Csapo, Bence; Kolovetsiou-Kreiner, Vassiliki; Mayer-Pickel, Karoline; Reif, Philipp; Stern, Christina; Ulrich, Daniela; Lang, Uwe; Obermayer-Pietsch, Barbara; Cervar-Zivkovic, Mila
• Is Part Of: Journal of maternal-fetal & neonatal medicine. Volume 31:Number 5(2018)
• Page Start: 549
• Page End: 552
• Publication Date: 2018-03-04
• Subjects: Preeclampsia -- first-trimester screening -- aspirin -- low-dose acetylsalicylic acid; Obstetrics -- Periodicals; Perinatology -- Periodicals; Infants (Newborn) -- Diseases -- Periodicals; Neonatology -- Periodicals; 618.2
• DOI: 10.1080/14767058.2017.1291621
• Languages: English
• ISSNs: 1476-7058

Abstract

Abstract: We analyzed outcome of women screened for preeclampsia with two different multifactorial risk algorithms (Predictor ® Software by PerkinElmer, PerkinElmer, Waltham, MA; PERK-group: n = 214 and Viewpoint ® by GE Healthcare, Dornstadt, Germany; VIEW-group: n = 209) in first trimester. Women at high risk for developing preeclampsia were advised to take low-dose acetylsalicylic acid (LDA). Screening positive rates for early onset preeclampsia differed significantly between the two groups (7.9% versus 26.3%; p = 0.000). According the clinical use of screening test criteria, LDA was prescribed in 63 (29.4%) women in the PE-group and 55 (26.3%) in the VP-group ( p = 0.516). There were no differences in onset of preeclampsia [4 (1.9%) versus 6 (2.9%); p = 0.540]. No early or severe preeclampsia occurred in the whole population.