Few-layered MoSe2 nanosheets as an efficient peroxidase nanozyme for highly sensitive colorimetric detection of H2O2 and xanthine. Issue 1 (6th December 2017)

• Record Type: Journal Article
• Authors: Wu, Xiaoju; Chen, Tongming; Wang, Jianxing; Yang, Guowei
• Is Part Of: Journal of materials chemistry. Volume 6:Issue 1(2017)
• Page Start: 105
• Page End: 111
• Publication Date: 2017-12-06
• Subjects: Materials -- Periodicals; Chemistry, Analytic -- Periodicals; Biomedical materials -- Research -- Periodicals; 543.0284
• DOI: 10.1039/c7tb02434g
• Languages: English
• ISSNs: 2050-750X

Abstract

Abstract : MoSe2 nanosheets possess intrinsic peroxidase-like activity and are applied to H2 O2 and xanthine detection with high sensitivity and selectivity. Abstract : Molybdenum-containing and selenium-containing enzymes are generally prevalent in the biosphere, and the active sites of these involve molybdenum and selenium respectively. Herein, we for the first time demonstrated that few-layered molybdenum selenide (MoSe2 ) nanosheets possess intrinsic peroxidase-like activity. The few-layered MoSe2 nanosheets were prepared by a simple liquid exfoliation method. The catalytic process of the MoSe2 nanosheets accords with the Michaelis–Menten behavior and they have a higher affinity to both TMB and H2 O2 compared to HRP. In addition, we established that the MoSe2 nanosheets catalyze the oxidation of TMB by promoting the electron transfer process from TMB to H2 O2 . More importantly, we applied the MoSe2 nanosheets to the field of biological detection by developing a highly sensitive and selective colorimetric detection of H2 O2 and xanthine concentration. With these advantages, the few-layered MoSe2 nanosheets have critical potential in the diagnostics and biomedical fields.